Download e-book for kindle: Aging: The Paradox Of Life: The biological reasons for aging by Robin Holliday (auth.)

By Robin Holliday (auth.)

ISBN-10: 1402056400

ISBN-13: 9781402056406

ISBN-10: 1402056419

ISBN-13: 9781402056413

For centuries humans were questioned through the inevitability of human getting older. for many of the second one half the 20th century getting older remained a secret, or an unsolved organic challenge. on the finish of the 20 th century a outstanding clinical discovery emerged. It was once no longer a unmarried discovery within the ordinary experience, since it used to be in keeping with a chain of significant interconnected insights over fairly an extended time period. those insights made it attainable for the first actual time to appreciate the organic purposes for getting older in animals and guy. it might already be stated, besides the fact that, that the numerous observations and insights that designate getting older usually are not approved as validated wisdom for a very long time. the sphere remains to be choked with scientists, and non-scientists, who're simply chuffed to move on speculating in regards to the "mystery" of getting older. the purpose of this booklet is to dispel lack of awareness through explaining in non-technical language what are the explanations for getting older and the parable of over the top prolongation of life.

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Extra resources for Aging: The Paradox Of Life: The biological reasons for aging are now well understood

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Such enzymes are an essential part of our digestive system, but within cells their role is much more subtle and discerning. They have to recognise abnormal molecules, and leave normal ones intact. This ability to discern abnormal and normal is only partly understood, but there is no doubt that it is an efficient process in all cells. The turnover of proteins occurs continuously during normal metabolism; many amino acids are re-utilised in the synthesis of new protein molecules, but some are degraded and end up as urea.

Some plants have evolved certain mechanical defences, but their main defence depends on chemistry. Most have developed the means of synthesising chemicals which are toxic to animals, so the latter learn to avoid eating them. Obviously all plants do not get eaten, nor do all animals die from plant toxins, so there is a dynamic balance between them. One part of this interaction is the ability of animals to detoxify harmful chemicals in their diet, which is a particularly important function of the liver.

Another maintenance mechanism, which has only become fully apparent in the last few years, is a special process called apoptosis to get rid of unwanted cells. This is a cell suicide mechanism in which the DNA is fragmented, the cell shrinks, and is ingested by scavenging cells known as macrophages. It occurs during normal development of the organism, for example in the central nervous system, or the immune system, but a better known instance is the regression of the tadpoles Maintenance of the Body 25 tail as it changes into a frog.

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Aging: The Paradox Of Life: The biological reasons for aging are now well understood by Robin Holliday (auth.)


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